To find out how this drug might interact with something else zoloft generic youre taking, talk to your doctor or pharmacist. Pharmacokinetics Absorption Following oral once-daily zoloft dosing over the range of 50 to 200 mg for 14 days, mean peak plasma concentrations (Cmax) of sertraline occurred between.5.4 hours post-dosing. Lexapro is prescribed to treat depression and generalized anxiety disorder. Zoloft is prescribed to treat depression, obsessive compulsive disorder, and several other mental health conditions. Hello AngieGutterman. I had the same problem when I was on zoloft. I suggest taking desyrel (trazodone). It is an anti-depressant, it will certainly sedate you, and help you fall asleep and unlike the benzodiazepine, kind or sort of sleeping medications, are not as prone to be habit forming. Zoloft is the brand name of sertraline, an antidepressant used to treat major depressive disorders. Zoloft is in a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). Sertraline (Zoloft) is an inexpensive drug used to treat depression. It may also be used to treat obsessive compulsive disorder, panic disorder, post-trauma stress, premenstrual dysphoric disorder , or social anxiety. What other drugs will affect Zoloft? Taking Zoloft with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking a sleeping pill, narcotic medication, muscle relaxer, or medicine for anxiety, depression, or seizures. What should I discuss with my healthcare provider before taking sertraline (Zoloft)? You should not use sertraline if you are allergic to it, or if you also take pimozide. ZOLOFT has helped treat the following conditions in adults: Major Depressive Disorder (MDD), Obsessive-Compulsive Disorder (OCD), Panic Disorder, Posttraumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), and Social Anxiety Disorder. See risks & benefits. Learn more about ZOLOFT® (sertraline HCl), a prescription treatment for depression. Effexor (venlafaxine) effectively treats depression, anxiety, and panic disorder. Effexor (venlafaxine) causes more sleepiness than other antidepressants, so it's beneficial for people who have trouble sleeping.